There are BSc and MSc student projects available in our group.
Interested? Feel free to send me an email (m.g.j.de.vos[at]rug.nl) for more information.
Interactions between bacteria from urinary tract infections
Urinary tract infections in the elderly people are often caused by more than one pathogenic bacterial species. We have recently discovered that these bacteria that cause urinary tract infections interact with each other, they ‘help’ each other to grow, or they ‘fight’ for food resources. In addition, these interactions seem to modulate the tolerance to clinically used antibiotics.
Research question 1:
How do commensal bacteria, isolated from healthy people, interact with pathogens that cause urinary tract infections?
Research question 2:
Can bacterial interactions affect the evolutionary trajectories leading to antibiotic resistance?
Research question 3:
Does the environment change bacterial interactions?
Subquestion: does a host change bacterial interactions?
Research question 4:
Do bacterial interactions affect HGT?
Research question 5:
Can chatty bacteria resolve urinary tract infections?
Computational MSc project in collaboration with Chrats Melkonian (UU) and Justin van der Hooft (WUR)